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Index > Protein center > Fam20b(Gene name) > Mouse
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  • Fam20b (Gene name),
  • Glycosaminoglycan xylosylkinase (Protein name ),  XYLK_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fam20b;
    Protein name:
    Glycosaminoglycan xylosylkinase;
    Alternative:
    Xylose kinase;Protein FAM20B;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-o-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    409
    Sequence:
    50:
    MKLKQRVVLL | AILLVIFIFT | KVFLIDNLDT | SAANREDQRA | FHRMMTGLRV | 
    100:
    ELVPKLDHTL | QSPWEIAAQW | VVPREVYPEE | TPELGAIMHA | MATKKIIKAD | 
    150:
    VGYKGTQLKA | LLILEGGQKV | VFKPKRYSRD | YVVEGEPYAG | YDRHNAEVAA | 
    200:
    FHLDRILGFR | RAPLVVGRYV | NLRTEVKPVA | TEQLLSTFLT | VGNNTCFYGK | 
    250:
    CYYCRETEPA | CADGDMMEGS | VTLWLPDVWP | LQKHRHPWGR | TYREGKLARW | 
    300:
    EYDESYCDAV | KKTSPYDSGP | RLLDIIDTAV | FDYLIGNADR | HHYESFQDDE | 
    350:
    GASMLILLDN | AKSFGNPSLD | ERSILAPLYQ | CCIIRVSTWN | RLNYLKNGVL | 
    400:
    KSALKSAMAH | DPISPVLSDP | HLDTVDQRLL | NVLATIKQCT | DQFGTDTVLV | 
    409:
    EDRMPLSHL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Glycosaminoglycan xylosylkinase
    Cat.:
    E14748h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Glycosaminoglycan xylosylkinase
    Cat.:
    E14748m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Glycosaminoglycan xylosylkinase
    Cat.:
    U14748h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Glycosaminoglycan xylosylkinase
    Cat.:
    U14748m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Glycosaminoglycan xylosylkinase
    Polyclonal Antibody for Mouse Glycosaminoglycan xylosylkinase
    Monoclonal Antibody for Mouse Glycosaminoglycan xylosylkinase
    Monoclonal Antibody for Mouse Glycosaminoglycan xylosylkinase
    Protein for Mouse Glycosaminoglycan xylosylkinase
    Protein for Mouse Glycosaminoglycan xylosylkinase

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Head.
      tissue: Spinal cord.
    2. 2.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Colon.
      tissue: Kidney.
    4. 4.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 142-409
      tissue: Embryonic tail.
    5. 5.
      "Whole-exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome."
      O'Sullivan J. , Bitu C.C. , Daly S.B. , Urquhart J.E. , Barron M.J. , Bhaskar S.S. , Martelli-Junior H. , dos Santos Neto P.E. , Mansilla M.A. , Murray J.C. , Coletta R.D. , Black G.C. , Dixon M.J.
      Am. J. Hum. Genet.88:616-620(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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